تفاعل #355066

معادلة التفاعل

triethylamine

adamantane carboxylic acid chloride

m-trifluoromethylaniline

→

title product

N-(3-Trifluoromethylphenyl)-1-adamantanecarboxamide

المذيبات

methylene chloride hexane

ظروف التفاعل

المعالجة

1. 1
   أخرىCrystallize the residue
2. 2
   أخرىobtained

الإجراء التجريبي

Subject 2.0 g. of adamantane carboxylic acid chloride, 1.60 (10 mmoles) of m-trifluoromethylaniline and 5.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from a methylene chloride-hexane mixture to obtain the title product, m.p. 171°-174°C.

المصدر