تفاعل #354576

معادلة التفاعل

sodium thiocyanate

α, 2'-dichloro-4-biphenylylacetic acid

→

α-thiocyanato-2'-chloro-4-biphenylylacetic acid

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe reaction mixture is filtered
2. 2
   غسيلwashed with absolute ethanol
3. 3
   أخرىThe filtrate is evaporated to dryness
4. 4
   workup.DISSOLUTIONthe residue is dissolved in 250 ml
5. 5
   غسيلof ether and washed several times with water
6. 6
   تجفيفThe ether is then dried
7. 7
   أخرىevaporated to dryness

الإجراء التجريبي

To a solution of 300 ml. of anhydrous ethanol and 0.15 moles of sodium thiocyanate is added 35 g. (0.12 moles) of α, 2'-dichloro-4-biphenylylacetic acid and stirred for 15 hours. The reaction mixture is filtered and washed with absolute ethanol. The filtrate is evaporated to dryness, the residue is dissolved in 250 ml. of ether and washed several times with water. The ether is then dried and evaporated to dryness to obtain α-thiocyanato-2'-chloro-4-biphenylylacetic acid.

المصدر