تفاعل #352736

معادلة التفاعل

decanyl chloroformate

N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide

→

phthalimide hydrochloride

المذيبات

ether

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas warmed on the steam bath for 15 minutes
2. 2
   ترشيحThe resulting solid was filtered

الإجراء التجريبي

A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-2-[4-(1-decanoxy-6-fluoro-1 H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.

المصدر