تفاعل #351232

معادلة التفاعل

tetrazole

5-Cyanocyclopentyl tetrazole

triethylamine

1-bromo dodecane

→

5-Cyanocyclopentyl-2-dodecyl-2H-tetrazole

المذيبات

acetonitrile

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe solution was heated
2. 2
   درجة الحرارةto reflux

الإجراء التجريبي

The tetrazole (b) obtained above (11.0 g; 0.067 moles) was dissolved in acetonitrile (150 mL) containing one equivalent of triethylamine (6.8 g; 0.067 moles). The solution was heated to reflux followed by the addition of 1-bromo dodecane (16.8 g; 0.067 moles). Isolation of the 2-isomer was achieved employing the same conditions described for Example 11.

المصدر