تفاعل #349359

معادلة التفاعل

3-[(2-aminoethyl)thiomethyl]isoxazole

hydrobromide

1-nitro-2,2-bis-methylthioethylene

→

1-nitro-2-methylthio-2-[2-(3-isoxazolylmethylthio)ethylamino]ethylene

ظروف التفاعل

الإجراء التجريبي

By the procedure of Example 8(i), 3-[(2-aminoethyl)thiomethyl]isoxazole (from the hydrobromide (3.7 g)) is reacted with 1-nitro-2,2-bis-methylthioethylene (3.5 g) to give 1-nitro-2-methylthio-2-[2-(3-isoxazolylmethylthio)ethylamino]ethylene (3.6 g) which, on reaction with methylamine by the procedure of Example 8(ii) gives the title product (3.0 g).

المصدر