تفاعل #349085

معادلة التفاعل

4-chloro-3,5-dinitrobenzonitrile

phosphorus oxychloride

toluene

→

4-chloro-3,5-diaminobenzonitrile

المردود 80.0%

المذيبات

toluene water

ظروف التفاعل

الإجراء التجريبي

By reaction with ammonia at about 0° C. to about 20° C., 4-chloro-3,5-dinitrobenzoic acid amide is obtained which is converted into 4-chloro-3,5-dinitrobenzonitrile by reaction with phosphorus oxychloride in boiling toluene. By reduction in boiling toluene/water with iron, 4-chloro-3,5-diaminobenzonitrile (melting point about 172° C.) is obtained in about 80% yield.

المصدر