تفاعل #347277

معادلة التفاعل

(Z)-1-(3-nitro-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl) ethene

→

intended compound

المردود 49.1%

(Z)-1-(3-amino-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl) ethene

المردود 49.1%

المذيبات

acetic acid

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction liquid
2. 2
   ترشيحwas filtered
3. 3
   تركيزconcentrated
4. 4
   أخرىpurified by silica gel column chromatography (dichloromethane:hexane=2.1 by volume)

الإجراء التجريبي

65 mg of (Z)-1-(3-nitro-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl) ethene were dissolved in 4 ml of acetic acid and 4 ml of dichloromethane, and 300 mg of zinc were added thereto and stirred for one hour. The reaction liquid was filtered, concentrated and purified by silica gel column chromatography (dichloromethane:hexane=2.1 by volume) to obtain 29 mg of the intended compound. The yield was 46.5%.

المصدر