تفاعل #346849

معادلة التفاعل

2,6-dimethylquinoline

butane sultone

→

4-[2,6-dimethyl-1-quinolinio]butane sulfonate

المردود 94.3%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةWhile cooling
2. 2
   أخرىcrystallization
3. 3
   workup.WAITwas conducted for 30 minutes
4. 4
   ترشيحThe resulting crystal was recovered by filtration
5. 5
   غسيلwashed with acetone
6. 6
   أخرىdried

الإجراء التجريبي

After 72.3 g (0.46 mol) of 2,6-dimethylquinoline and 188 g (1.4 mol) of butane sultone were heated at 145° C. with stirring for 4 hours, the mixture was allowed to cool to room temperature, and 500 ml of acetone was added thereto. While cooling, crystallization was conducted for 30 minutes. The resulting crystal was recovered by filtration, washed with acetone and dried to obtain 127.3 g (yield: 94%) of 4-[2,6-dimethyl-1-quinolinio]butane sulfonate.

المصدر