تفاعل #346130

معادلة التفاعل

N2

caprinaldehyde

methyl vinyl ketone

KOH

N2

triethylamine

→

Tetradecane-2,5-dione

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITION1 are introduced into a 250 ml three-necked flask
2. 2
   أخرىequipped with a stirrer
3. 3
   أخرىis brought to 80° C
4. 4
   workup.DISSOLUTIONThe initially undissolved catalyst dissolves
5. 5
   أخرىafter some time triethylamine hydrochloride precipitates
6. 6
   درجة الحرارةit is first cooled

الإجراء التجريبي

78.1 g (0.5 mol) of caprinaldehyde, 35.1 g (0.5 mol) of methyl vinyl ketone and 13.5 g (0.05 mol) of Cat. 1 are introduced into a 250 ml three-necked flask equipped with a stirrer, reflux condenser (high efficiency, KOH drying tube) and N2 inlet. After adding 40.4 g (0.4 mol) of triethylamine, a N2 atmosphere is set up, the mixture is stirred and the surrounding oil bath is brought to 80° C. The initially undissolved catalyst dissolves and after some time triethylamine hydrochloride precipitates. The mixture is kept at 80° C for 12 hours. For working up, it is first cooled, and then the procedure described in Example 21 is followed. Tetradecane-2,5-dione is obtained. Recrystallization from methanol.

المصدر