تفاعل #343463

معادلة التفاعل

3-mercapto-1,2,4-triazole

sodium methoxide

cyclopropylmethyl bromide

→

3-cyclopropylmethylthio-1,2,4-triazole

المردود 99.1%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter removal of the solvent
2. 2
   استخلاصthe residue was extracted with chloroform
3. 3
   أخرىEvaporation of the chloroform
4. 4
   استخلاصextract

الإجراء التجريبي

To a solution of 3-mercapto-1,2,4-triazole (7.1 g) and sodium methoxide (3.8 g) in methanol (100 ml), there was added cyclopropylmethyl bromide (9.5 g), and the resultant mixture was allowed to stand at room temperature for 10 hours. After removal of the solvent, the residue was extracted with chloroform. Evaporation of the chloroform extract gave 10.8 g of 3-cyclopropylmethylthio-1,2,4-triazole. Yield, 99%. M.P., 69°-70° C.

المصدر