تفاعل #341088

معادلة التفاعل

5-aminothiazole 2-mercaptoacetic acid ethyl ester

{2-[3-Cyclohexyl-3-(4,4-difluoro-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester

cyclohexyl-(4,4-difluoro-cyclohexyl)-amine

→

title compound

{2-[3-Cyclohexyl-3-(4,4-difluoro-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid

ظروف التفاعل

المعالجة

1. 1
   أخرىHydrolysis

الإجراء التجريبي

{2-[3-Cyclohexyl-3-(4,4-difluoro-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester prepared using general procedures (A) and (B) using cyclohexyl-(4,4-difluoro-cyclohexyl)-amine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

المصدر