تفاعل #341013

معادلة التفاعل

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

isopropylamine

sodium triacetoxyborohydride

→

desired product

المردود 42.0%

1,1-Dicyclohexyl-3-[5-(isopropylamino-methyl)-thiazol-2-yl]-urea

المردود 42.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىPrepared

الإجراء التجريبي

Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (100 mg. 0.30 mmol), isopropylamine (30 μL, 0.36 mmol) and sodium triacetoxyborohydride (101 mg, 0.48 mmol) to afford 47 mg (42%) of the desired product after purification.

المصدر