تفاعل #339612

معادلة التفاعل

4-bromo-biphenyl

Chlorosulfonic acid

→

4′-bromo-biphenyl-4-sulfonic acid

المردود 92.0%

المذيبات

chloroform

ظروف التفاعل

المعالجة

1. 1
   أخرىA 500 mL round-bottom-flask equipped with an addition funnel
2. 2
   أخرىthen purged with nitrogen
3. 3
   workup.STIRRINGthen stirred for 1 hour
4. 4
   ترشيحThe resulting precipitate was collected by vacuum filtration
5. 5
   غسيلwashed with cold chloroform
6. 6
   أخرىdried under vacuum

الإجراء التجريبي

A 500 mL round-bottom-flask equipped with an addition funnel, stirring bar, and gas inlet was charged with 4-bromo-biphenyl (50 g, 0.215 mol) and chloroform (200 mL) then purged with nitrogen. Chlorosulfonic acid (18 mL, 0.27 mol) was added dropwise to the solution from the addition funnel then stirred for 1 hour. The resulting precipitate was collected by vacuum filtration, washed with cold chloroform, and dried under vacuum to give 61.97 g of 4′-bromo-biphenyl-4-sulfonic acid (92% yield).

المصدر