تفاعل #339549

معادلة التفاعل

acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester

diethyl ether pentane

→

title compound

4-(4-Methoxy-butyl)-pyridin-3-ol

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter cooling
2. 2
   ترشيحthe precipitate is collected by filtration

الإجراء التجريبي

A mixture of 39 mmol acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester in 20 ml acetic acid is heated to 70° C. for 30 minutes. After cooling, 75 ml of diethyl ether/pentane (1:5) is added and the precipitate is collected by filtration. The title compound is obtained from the solid by re-crystallization from toluene and identified based on its Rf value.

المصدر