تفاعل #335962

ord-33486a3cd4d94443b18c2027e6340b8a

معادلة التفاعل

C[Si](C)(C)Cl
chlorotrimethylsilane
[Ca]
calcium
[Li+].[c-]1cccc2cc3ccccc3cc12
lithium anthracenide
[Ca+2].[I-].[I-]
calcium iodide
[Ca]
calcium
[Li+].[Li+].[c-]1ccccc1-c1[c-]cccc1
lithium biphenylide

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىto yield the silylated product

الإجراء التجريبي

Preformed lithium anthracenide was reacted with calcium iodide to prepare a soluble calcium species. This calcium species was added to chloromethylated polystyrene (DF=0.11) and stirred for 24 hours at room temperature. The corresponding calcium-substituted reagent was then reacted with chlorotrimethylsilane at room temperature to yield the silylated product; however, the yield was not optimized and was lower than the yield obtained from preformed lithium biphenylide (Table III, entry 4). Reaction of the calcium species with chloromethylated polystyrene at 0° C. for 6 hours resulted in a 100% loss of chlorine from the polymer. Subsequent reaction with benzaldehyde gave the corresponding secondary alcohol in 80% yield, compared to the 100% yield when calcium biphenylide was used (Table III, entry 6).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05211886uspto-grants-1993_05