تفاعل #3339

معادلة التفاعل

2-dimethylaminobenzylchloride hydrochloride

5-ethyl-5-methyl-4-thiohydantoin

→

desired compound

4-(2-dimethylaminobenzylthio)-5-ethyl-5-methyl-3-imidazolin-2-one

ظروف التفاعل

المعالجة

1. 1
   أخرىCrystallization from diethyl ether-n-hexane

الإجراء التجريبي

In the present Example, 2.3 g of 2-dimethylaminobenzylchloride hydrochloride and 1.5 g of 5-ethyl-5-methyl-4-thiohydantoin were reacted following the procedure used in Example 36. Crystallization from diethyl ether-n-hexane gave the desired compound in the form of a needle-like crystal. The yield of this compound was 1.9 g with a yield ratio of 68.6%, and the melting point was 111°-113° C.

المصدر