تفاعل #332490

معادلة التفاعل

Dibenzylamine

(S)-epichlorohydrin

→

colorless oil

المردود 94.9%

(S)-1-chloro-3-(dibenzylamino)propan-2-ol

المردود 94.9%

المذيبات

methylene dichloride

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGThe mixture was stirred at room temperature (25° C.) for 20 hours
2. 2
   ترشيحFiltered
3. 3
   أخرىthe solvent was evaporated

الإجراء التجريبي

Dibenzylamine (39.4 g, 0.20 mol) was added to 100 mL of methylene dichloride and stirred for 30 minutes. (S)-epichlorohydrin (21 g, 0.23 mol) was then added. The mixture was stirred at room temperature (25° C.) for 20 hours. Filtered, and the solvent was evaporated to provide 55 g of colorless oil in 93% yield.

المصدر