تفاعل #324808

ord-cadc2fec94e24b23a7aeec34b9f06cbe

معادلة التفاعل

Cc1cncc(B(O)O)c1
5-methyl-pyridine-3-boronic acid
Cc1cc(I)cc(C)c1Br
2-bromo-5-iodo-1,3-dimethyl-benzene
Cc1cncc(-c2cc(C)c(Br)c(C)c2)c1
title compound
Cc1cncc(-c2cc(C)c(Br)c(C)c2)c1
3-(4-Bromo-3,5-dimethyl-phenyl)-5-methyl-pyridine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound is prepared from 5-methyl-pyridine-3-boronic acid and 2-bromo-5-iodo-1,3-dimethyl-benzene following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 9): tR=0.93 min; Mass spectrum (ESI+): m/z=276/278 (Br) [M+H]+.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08642585B2uspto-grants-2014_02