تفاعل #322161

معادلة التفاعل

4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl

trifluoroacetic acid

→

4-(Carboxymethyloxy)-4'-cyano-biphenyl

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   أخرىthe reaction mixture is evaporated to dryness
2. 2
   أخرىthe solid residue is triturated with water

الإجراء التجريبي

32.9 g of 4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl dissolved in 250 ml of methylene chloride is mixed slowly with 137 ml of trifluoroacetic acid. After stirring for 3 hours, the reaction mixture is evaporated to dryness and the solid residue is triturated with water.

المصدر