تفاعل #321092

ord-38cbc2b51b694f17958edcfa41013f99

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةwas warmed on the steam bath for 15 minutes
  2. 2
    ترشيحThe resulting solid was filtered

الإجراء التجريبي

A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05593995uspto-grants-1997_01