تفاعل #320414

ord-ca151da2bdc54daea11f816ecc6f1704

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةwas warmed on the steam bath for 15 minutes
  2. 2
    ترشيحThe resulting solid was filtered

الإجراء التجريبي

A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1 H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-[2-[4-(1 -decanoxy-6-fluoro-1 H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05591745uspto-grants-1997_01