تفاعل #319114

معادلة التفاعل

THF

4-phenylcyclohexanone

→

4-phenyl-1-methylenecyclohexane

المردود 78.0%

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter a homogeneous solution was formed
2. 2
   workup.ADDITION1 molar equivalent (2 milliliters) of TEAL was added
3. 3
   workup.STIRRINGAfter 3 hours of stirring

الإجراء التجريبي

BDAM (3.00 grams) was suspended in 40 milliliters of toluene and 2 molar equivalents of THF were added at 0° C. After a homogeneous solution was formed, 1 molar equivalent (2 milliliters) of TEAL was added. After 10 minutes of stirring, 2.50 grams of 4-phenylcyclohexanone were added. After 3 hours of stirring, the reaction mixture was hydrolyzed and worked up as described in Example 1. A total of 1.93 grams of 4-phenyl-1-methylenecyclohexane was isolated (78% yield).

المصدر