تفاعل #318196

معادلة التفاعل

sulfuric acid

4'-hydroxybiphenyl-4-carboxylic acid

ethanol

→

4'-hydroxybiphenyl-4-carboxylic acid ethyl ester

المردود 97.0%

ظروف التفاعل

المعالجة

1. 1
   تركيزThe reaction solution was concentrated
2. 2
   أخرىpurified by column chromatography

الإجراء التجريبي

1 ml of conc. sulfuric acid was added to an ethanol solution of 0.1 mole(21.4 g) of 4'-hydroxybiphenyl-4-carboxylic acid, and stirred for 18 hours. The reaction solution was concentrated, and then purified by column chromatography, to obtain 22.8 g of 4'-hydroxybiphenyl-4-carboxylic acid ethyl ester [m.p. 144.4°-145.6° C⟧ (yield: 97%)

المصدر