تفاعل #3171

ord-1353d03acc334b3781453676e9c404d0

معادلة التفاعل

Fc1cc(-c2ccsc2)cc(F)c1F
3(3,4,5-trifluorophenyl)thiophene
Fc1cc(F)cc(Br)c1
1-bromo-3,5-difluorobenzene
Fc1cc(Br)cc(F)c1F
1-bromo-3,4,5-trifluorobenzene
Fc1cc(F)cc(-c2ccsc2)c1
3(3,5-difluorophenyl)thiophene

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The same procedures set forth above in Example (1)(a) for synthesizing 3(3,4,5-trifluorophenyl)thiophene were followed, with the exception that 1-bromo-3,5-difluorobenzene was substituted for 1-bromo-3,4,5-trifluorobenzene as the 1-bromo-substituted fluorobenzene.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05733683uspto-grants-1998_03