تفاعل #3158

معادلة التفاعل

2-octylbenzofuran

→

2-octylcoumaran

المردود 94.6%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىfor 3 hours
2. 2
   أخرىAfter the reaction
3. 3
   أخرىthe catalyst was removed by filtration
4. 4
   تركيزthe filtrate was concentrated under reduced pressure
5. 5
   أخرىto obtain a residue
6. 6
   أخرىThe residue was purified by silica gel column chromatography (eluent:hexane)

الإجراء التجريبي

Then, 44 g of 2-octylbenzofuran was dissolved in 440 ml of ethanol. To the solution 35 g of 10%-palladium-carbon was added to effect catalytic reduction for 3 hours sunder normal pressure. After the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to obtain a residue. The residue was purified by silica gel column chromatography (eluent:hexane) to obtain 42 g of liquid 2-octylcoumaran (Yield: 94.6%).

المصدر