تفاعل #3143

معادلة التفاعل

4,6-dichloro-2-methyl-5-nitropyrimidine

→

4,6-dichloro-2-methyl-5-aminopyrimidine

المذيبات

toluene

ظروف التفاعل

الإجراء التجريبي

The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.

المصدر