تفاعل #312137

معادلة التفاعل

6-bromohexanoic acid methyl ester

potassium cyanate

methanol

→

6-methoxycarbonylaminohexanoic acid methyl ester

المردود 77.0%

المذيبات

DMF

ظروف التفاعل

الإجراء التجريبي

The reaction of 10.45 grams of 6-bromohexanoic acid methyl ester with 6.08 grams of potassium cyanate and 2.7 grams of methanol in 50 ml DMF following the procedure of Example 1 gave 7.82 grams (76.9%) of 6-methoxycarbonylaminohexanoic acid methyl ester having a boiling point of 104° C./0.0013 mbar.

المصدر