تفاعل #307844

ord-f03fbe80d2d24fa1aa6419acf96d2586

معادلة التفاعل

CS(C)(=O)=O
(methylsulphonyl)methane
CC(C)(C)OC(=O)/N=C/c1cccc(C(F)(F)F)c1
compound
CC(C)(C)OC(=O)/N=C/c1cccc(C(F)(F)F)c1
tert-Butyl {(E)-[3-(trifluoromethyl)phenyl]methylidene}carbamate
→
CC(C)(C)OC(=O)NC(CS(C)(=O)=O)c1cccc(C(F)(F)F)c1
title compound
CC(C)(C)OC(=O)NC(CS(C)(=O)=O)c1cccc(C(F)(F)F)c1
tert-Butyl {2-(methylsulphonyl)-1-[3-(trifluoromethyl)phenyl]ethyl}carbamate

المتفاعلات

CS(C)(=O)=O
(methylsulphonyl)methane
CC(C)(C)OC(=O)/N=C/c1cccc(C(F)(F)F)c1
compound
CC(C)(C)OC(=O)/N=C/c1cccc(C(F)(F)F)c1
tert-Butyl {(E)-[3-(trifluoromethyl)phenyl]methylidene}carbamate

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

From 1.50 g (15.9 mmol) of (methylsulphonyl)methane and 1.45 g (5.31 mmol) of the compound from Example 11A, using the same process as for Example 117A, 535 mg (27% of theory) of the title compound were obtained.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08202895B2uspto-grants-2012_06