تفاعل #3066

معادلة التفاعل

ethyl 3-bromo-4-methylbenzoate

NBS

benzoyl peroxide

→

ethyl 3-bromo-4-bromomethylbenzoate

المذيبات

CCl4

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 4 h
2. 2
   ترشيحprocessed by filtration and chromatography

الإجراء التجريبي

A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.

المصدر