تفاعل #306096
ord-2591e7a6362b4696b0d6b308e6a8dcff
معادلة التفاعل
3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid
intermediate 1
3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid
azepan-1-ylamine
→
N-azepan-1-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىLC/MS [8.99 min; 455 (M+1)]
الإجراء التجريبي
N-azepan-1-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.45 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 6.2 mmol of azepan-1-ylamine. LC/MS [8.99 min; 455 (M+1)]