تفاعل #3029

معادلة التفاعل

1-chloro-2,4-dinitrobenzene

sodium carbonate

dioctadecylamine

dimethylformamide

→

N,N-dioctadecyl-2,4-dinitrobenzenamine

المردود 87.2%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas heated to 80°-90° C. under a nitrogen atmosphere for 1 h
2. 2
   استخلاصextracted with ether
3. 3
   غسيلThe extracts were washed with water
4. 4
   تجفيفdried over magnesium sulfate
5. 5
   أخرىThe solvent was removed
6. 6
   أخرىthe solid recrystallized

الإجراء التجريبي

A mixture of 1-chloro-2,4-dinitrobenzene (Aldrich, 2.02 g, 10 mmol), sodium carbonate (1.27 g, 12 mmol), dioctadecylamine (Pfaltz & Bauer, 6.26 g, 12 mmol) and dry dimethylformamide (10 mL) was heated to 80°-90° C. under a nitrogen atmosphere for 1 h. The cooled mixture was diluted with water and extracted with ether. The extracts were washed with water and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give N,N-dioctadecyl-2,4-dinitrobenzenamine (6.0 g, 87%): mp 55.5°-57.5° C.

المصدر