تفاعل #3028

معادلة التفاعل

hydrochloric acid

2,4-dinitrophenol

octadecyl bromide

sodium carbonate

→

1-octadecyloxy-2,4-dinitrobenzene

المردود 79.1%

المذيبات

dimethylformamide

water

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted with ether
2. 2
   غسيلThe extracts were washed with water and brine
3. 3
   تجفيفdried over magnesium sulfate
4. 4
   أخرىThe solvent was removed
5. 5
   أخرىthe solid recrystallized

الإجراء التجريبي

A mixture of 2,4-dinitrophenol (85 wt %, 6.72 g, 31 mmol), octadecyl bromide (20.7 g, 62 mmol), sodium carbonate (6.57 g, 62 mmol) and dimethylformamide (31 mL) was heated to 100° C. under a nitrogen atmosphere for 22 h. The cooled mixture was diluted with water (200 mL), acidified with 10N hydrochloric acid (50 mL) and extracted with ether. The extracts were washed with water and brine, and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give 1-octadecyloxy-2,4-dinitrobenzene (10.7 g, 79%): mp 63.5°-64.0° C.

المصدر