تفاعل #2618

معادلة التفاعل

N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-3-methoxy-N-(2-methoxyphenyl)benzamide

oxalic acid

→

title compound

المردود 79.2%

N-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}-3-methoxy-N-(2-methoxyphenyl)benzamide oxalate

المردود 79.2%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىmethanol was removed by evaporation
2. 2
   ترشيحcollected by filtration

الإجراء التجريبي

N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-3-methoxy-N-(2-methoxyphenyl)benzamide (107 mg, 0.218 mmol) was dissolved in methanol (10 ml) to which was subsequently added oxalic acid (19.7 mg, 0.218 mmol). After 5 minutes of stirring at room temperature, methanol was removed by evaporation, and the resulting residue was solidified in ether (5 ml) and collected by filtration to obtain 100 mg (79.2%) of the title compound in a colorless powder form.

المصدر