تفاعل #2513713

معادلة التفاعل

3-oxo-6-pyridin-4-yl-2,3-dihydro-pyridazine-4-carboxylic acid hydrazide

thioacetamide

triethylamine

pyridine

→

4-(5-Methyl-4H-[1,2,4]triazol-3-yl)-6-pyridin-4-yl-2H-pyridazin-3-one

المذيبات

butanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةis refluxed for 15 hours
2. 2
   درجة الحرارةAfter cooling
3. 3
   أخرىa solid precipitated
4. 4
   ترشيحis collected by filtration
5. 5
   غسيلwashed with cold isopropanol
6. 6
   أخرىdried in vacuo

الإجراء التجريبي

A mixture of 100 mg of 3-oxo-6-pyridin-4-yl-2,3-dihydro-pyridazine-4-carboxylic acid hydrazide, 130 mg thioacetamide, 87 mg triethylamine, 1 ml of pyridine and 5 ml of butanol is refluxed for 15 hours. After cooling and stirring at room temperature, a solid precipitated is collected by filtration, washed with cold isopropanol and dried in vacuo.

المصدر