تفاعل #2507841

معادلة التفاعل

2-propynyl 2,5-difluoro-4-(2-propynyloxy)benzoate

sodium hydroxide

hydrochloric acid

→

2,5-difluoro-4-(2-propynyloxy)benzoic acid

المردود 61.4%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحa produced solid was collected by filtration
2. 2
   أخرىThe solid was dried
3. 3
   غسيلwashed with hexane

الإجراء التجريبي

To a mixture of 20 ml of methanol and 20 ml of a 15% aqueous sodium hydroxide solution was added 7.3 g of 2-propynyl 2,5-difluoro-4-(2-propynyloxy)benzoate, and the mixture was stirred at 50° C. for 2 hours. The reaction mixture was added to hydrochloric acid, and a produced solid was collected by filtration. The solid was dried and then washed with hexane, and 3.8 g of 2,5-difluoro-4-(2-propynyloxy)benzoic acid was obtained.

المصدر