تفاعل #2490353

ord-de08c71ea8c3486b9a40b3917f880724

معادلة التفاعل

COC(=O)C1CCN1C1CCN(S(C)(=O)=O)CC1
methyl 1-(1-(methylsulfonyl)piperidin-4-yl)azetidine-2-carboxylate
O.[Li+].[OH-]
lithium hydroxide monohydrate
→
CS(=O)(=O)N1CCC(N2CCC2C(=O)[O-])CC1.[Li+]
lithium 1-(1-(methylsulfonyl)piperidin-4-yl)azetidine-2-carboxylate

المتفاعلات

COC(=O)C1CCN1C1CCN(S(C)(=O)=O)CC1
methyl 1-(1-(methylsulfonyl)piperidin-4-yl)azetidine-2-carboxylate
O.[Li+].[OH-]
lithium hydroxide monohydrate

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The reaction of methyl 1-(1-(methylsulfonyl)piperidin-4-yl)azetidine-2-carboxylate 19L and lithium hydroxide monohydrate yielded lithium 1-(1-(methylsulfonyl)piperidin-4-yl)azetidine-2-carboxylate as light brown solid (quant.). MS ISP (m/e): 263.1 (100) [(M+H)]+.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08802665B2uspto-grants-2014_08