تفاعل #2490347

ord-23aaea6d18eb492385b3381990d5707e

معادلة التفاعل

COC(=O)C1CCN1C1CCCCC1
methyl 1-(cyclohexyl)azetidine-2-carboxylate
O.[Li+].[OH-]
lithium hydroxide monohydrate
→
O=C([O-])C1CCN1C1CCCCC1.[Li+]
lithium 1-(cyclohexyl)azetidine-2-carboxylate

المتفاعلات

COC(=O)C1CCN1C1CCCCC1
methyl 1-(cyclohexyl)azetidine-2-carboxylate
O.[Li+].[OH-]
lithium hydroxide monohydrate

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The reaction of methyl 1-(cyclohexyl)azetidine-2-carboxylate 19A and lithium hydroxide monohydrate yielded lithium 1-(cyclohexyl)azetidine-2-carboxylate as a brown oil (quant). MS ISP (m/e): 184.2 (100) [(M+H)]+.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08802665B2uspto-grants-2014_08