تفاعل #2476801

معادلة التفاعل

Biaryl amine

tert-Butyl {4-[(4′-methanesulfonyl-4-methoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate

acid chloride

3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride

→

title compound

tert-Butyl {4-[(3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(4′-methanesulfonyl-4-methoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate

ظروف التفاعل

الإجراء التجريبي

Biaryl amine 103 (1.84 g, 3.66 mmol) is treated with acid chloride 8 (1.17 g, 4.38 mmol) using Method D to give the title compound.

المصدر