تفاعل #2470019

ord-89aa92c447cf425aaa9a9cf734ea9a19

معادلة التفاعل

Nc1nc2cccc(-c3ccoc3)n2n1
5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine
CCCCc1ccc(C(=O)O)cc1
4-butylbenzoic acid
CCCCc1ccc(C(=O)Nc2nc3cccc(-c4ccoc4)n3n2)cc1
title compound
CCCCc1ccc(C(=O)Nc2nc3cccc(-c4ccoc4)n3n2)cc1
4-butyl-N-[5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]benzamide

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared following procedure and work up described for example 2, but starting from 5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A2), 75 mg; 0.37 mmol; 1.0 eq.) and 4-butylbenzoic acid (80 mg; 0.45 mmol; 1.2 eq.) as a yellow foam (20 mg, 15%). HPLC, Rt: 4.45 min. (purity 82.6%). LC/MS, M+(ESI): 361.1, M−(ESI): 359.1.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08263595B2uspto-grants-2012_09