تفاعل #2468021

ord-f473e0b50a9e41cba1627851fb3bb644

معادلة التفاعل

NNc1ncc(F)cc1F
3,5-difluoro-2-hydrazinopyridine
CC(C)(C)OC(=O)NC(C)(C)C(=O)O
N-(tert-butoxycarbonyl)-2-methylalanine
CC(C)(C)OC(=O)NC(C)(C)C(=O)NNc1ncc(F)cc1F
tert-Butyl 1-(2-(3,5-difluoropyridin-2-yl)hydrazinyl)-2-methyl-1-oxopropan-2-ylcarbamate

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

This compound was prepared (66%) from 3,5-difluoro-2-hydrazinopyridine and N-(tert-butoxycarbonyl)-2-methylalanine following the experimental procedure described for the synthesis of Intermediate 21, step a.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08258122B2uspto-grants-2012_09