تفاعل #2468012

معادلة التفاعل

4-furan-3-yl-1-nitrobenzene

→

4-furan-3-yl-phenylamine

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe crude mixture is purified by column chromatography
2. 2
   workup.ADDITIONa solvent mixture of cyclohexane/ethyl acetate 50/50

الإجراء التجريبي

277 mg 4-furan-3-yl-1-nitrobenzene are dissolved in 40 ml of methanol and combined with 200 mg palladium/C. The suspension is shaken at 25° C. for 60 h under a H2 pressure of 5 bar. Then the solvent is eliminated in vacuo. The crude mixture is purified by column chromatography. The carrier material used is silica gel and the mobile phase used is a solvent mixture of cyclohexane/ethyl acetate 50/50. The suitable fractions are freed from the solvent in vacuo.

المصدر