تفاعل #2468002
ord-27600ec5354142cdb571a44664f174fa
معادلة التفاعل
triethylamine
chlorotriphenylmethane
(1H-imidazol-4-yl)-acetonitrile
Water
→
(1-trityl-1H-imidazol-4-yl)-acetonitrile
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىthe organic phase is separated off
- 2تجفيفdried with MgSO4
الإجراء التجريبي
2.5 g (1H-imidazol-4-yl)-acetonitrile are dissolved in 20 mL DMF. After the addition of 3.6 mL triethylamine and 7.25 g chlorotriphenylmethane the suspension is left for 60 h at RT with stirring. Water and ethyl acetate are added, the organic phase is separated off, dried with MgSO4 and the solvent is eliminated in vacuo.