تفاعل #2460284

معادلة التفاعل

4-Bromophenol

potassium carbonate

benzyl bromide

→

4-benzyloxybromobenzene

المذيبات

water

acetone

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe reaction was refluxed under nitrogen
2. 2
   درجة الحرارةAfter 5-6 hours of reflux
3. 3
   أخرىthe organic layer was separated
4. 4
   تجفيفdried over magnesium sulfate
5. 5
   أخرىevaporated to dryness
6. 6
   أخرىto afford a white fluffy powder

الإجراء التجريبي

4-Bromophenol (2 g, 0.0116 mol) in acetone (40 ml) was treated with potassium carbonate (1.91 g, 1.2 equivalents) and benzyl bromide (1.44 ml, 1.05 equivalents). The reaction was refluxed under nitrogen. After 5-6 hours of reflux, the reaction was cooled to room temperature and diluted with an equal volume of ethyl acetate. This was diluted further with water and the organic layer was separated, dried over magnesium sulfate and evaporated to dryness to afford a white fluffy powder. Yield=2.36 g (73%).

المصدر