تفاعل #2446143
ord-7d88b5859f3e4faea46e3a1e65aacc81
معادلة التفاعل
7-hydroxy-3,4,4a,8a-tetrahydro-1H-quinolin-2-one
NBS
→
6-Bromo-7-hydroxy-3,4,4a,8a-tetrahydro-1H-quinolin-2-one
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىThis intermediate was obtained
الإجراء التجريبي
This intermediate was obtained according to general procedure I from 7-hydroxy-3,4,4a,8a-tetrahydro-1H-quinolin-2-one (370 mg, 2.27 mmol) and NBS (424 mg, 2.38 mmol) after flash chromatography on silica gel (hexanes/ethyl acetate, 1/1, Rf=0.15) as white solid (500 mg, 2.07 mmol, 91%).