تفاعل #2446142

معادلة التفاعل

7-fluoro-3,4,4a,8a-tetrahydro-1H-quinolin-2-one

NBS

→

6-Bromo-7-fluoro-3,4,4a,8a-tetrahydro-1H-quinolin-2-one

ظروف التفاعل

المعالجة

1. 1
   أخرىThis intermediate was obtained

الإجراء التجريبي

This intermediate was obtained according to general procedure I from 7-fluoro-3,4,4a,8a-tetrahydro-1H-quinolin-2-one (92 mg, 0.56 mmol) and NBS (104 mg, 0.58 mmol) after flash chromatography on silica gel (hexanes/ethyl acetate, 5/1, Rf=0.27) as white solid (120 mg, 0.49 mmol, 88%).

المصدر