تفاعل #2383763

ord-dd422b610fdf444eaffdb5e45e3e760d

معادلة التفاعل

Cc1c[nH]nc1C
3,4-dimethylpyrazole
C=O
formalin
Cc1cn(CO)nc1C
solid
المردود 95.0%
Cc1cn(CO)nc1C
N-hydroxymethyl-3,4-dimethylpyrazole
المردود 95.0%

المتفاعلات

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىWater and methanol were then evaporated

الإجراء التجريبي

96 g (1.0 mol) of 3,4-dimethylpyrazole in 50 ml of methanol were dissolved in 100 g (1.0 mol) of formalin solution (30%) at room temperature. Water and methanol were then evaporated. The title compound remained as a white solid (yield 95%).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06488734B1uspto-grants-2002_12