تفاعل #2336540

معادلة التفاعل

carbazole

potassium carbonate

18-crown-6-ether

→

9-(2-pyridyl)carbazole

المردود 93.0%

المذيبات

o-dichlorobenzene

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةrefluxed under a nitrogen atmosphere for 10 hours
2. 2
   أخرىThereafter, copper and inorganic salts were removed
3. 3
   أخرىthe mixture was purified by column chromatography

الإجراء التجريبي

In 40 ml of o-dichlorobenzene as solvent, 3.94 g of carbazole, 7.26 g of 2-iondopyridine, 13.10 g of potassium carbonate, 3 g of copper powder, and 0.62 g of 18-crown-6-ether were mixed and refluxed under a nitrogen atmosphere for 10 hours. Thereafter, copper and inorganic salts were removed, and the mixture was purified by column chromatography. Consequently, ligand Hpcz (9-(2-pyridyl)carbazole) was obtained (opal powder, the yield: 93%). The following is the synthesis scheme (b-1).

المصدر