تفاعل #2336534

معادلة التفاعل

Water

2-Chlorothiophenol

potassium carbonate

DMF

→

title compound

3,6-Bis(2′-chlorophenylthio) phthalonitrile

ظروف التفاعل

المعالجة

1. 1
   ترشيحthen filtered
2. 2
   أخرىThe filter cake was purified by flash column chromatography (eluting 30% ethyl acetate:isohexane)

الإجراء التجريبي

2-Chlorothiophenol (12.50 g, 86.5 mmol), potassium carbonate (11.94 g, 86.5 mmol) and ditosylated dicyanohydroquinone (20.36 g, 43.5 mmol) in DMF (80 mL) were reacted as described above. Water (100 mL) was added and the mixture stirred for 1 hour then filtered. The filter cake was purified by flash column chromatography (eluting 30% ethyl acetate:isohexane) to give the title compound as a yellow solid (5.53 g, 13.4 mmol, 31%) [Found: C, 58.1%; H, 2.7%; N, 6.9%; S, 15.4%; Cl 16.6%; C20H10N2S2Cl2 requires C, 58.1%; H, 2.4%; N, 6.8%; S, 15.5%; Cl 17.2%]; MS (EI+) 412 (M+, 100%)

المصدر