تفاعل #2336533

معادلة التفاعل

2-Methylthiophenol

potassium carbonate

DMF

→

title compound

المردود 42.0%

3,6-Bis(2′-methylphenylthio) phthalonitrile

المردود 42.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىThe mixture was isolated
2. 2
   أخرىto give a yellow oil
3. 3
   أخرىThe material was purified by flash column chromatography (eluting 10% ethyl acetate:isohexane)

الإجراء التجريبي

2-Methylthiophenol (10.60 g, 85.5 mmol), potassium carbonate (11.82 g, 82.0 mmol) and ditosylated dicyanohydroquinone (20.00 g, 42.7 mmol) in DMF (75 mL) were reacted as described above. The mixture was isolated as described above to give a yellow oil. The material was purified by flash column chromatography (eluting 10% ethyl acetate:isohexane) to give the title compound as a yellow solid (8.85 g, 23.8 mmol, 42%). [Found: C, 70.7%; H, 4.6%; N, 7.5%; S, 17.2%; C22H16N2S2 requires C, 70.9%; H, 4.3%; N, 7.5%; S, 17.2%]; MS (EI+) 372 (M+, 100%), 357 (M-CH3, 8), 339 (20).

المصدر