تفاعل #2314279

معادلة التفاعل

bromopentane

→

2-Pentyl-1,3-butadiene

المذيبات

ammonium chloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةgradually warming to room temperature
2. 2
   workup.STIRRINGThe reaction mixture is stirred for 10 minutes, during which time the aqueous layer
3. 3
   استخلاصThe reaction mixture is then extracted with hexanes
4. 4
   تجفيفthe combined organic layers are dried over magnesium sulfate
5. 5
   أخرىThe solvent is carefully removed by rotary evaporation
6. 6
   أخرىto give 17 g of a colorless, malodorous liquid

الإجراء التجريبي

To a flask containing cuprous bromide (1.0 g) is added bromopentane (23 g) and tetrahydrofaran (154 mL). The solution is cooled to 0° C., and the Grignard reagent 1B is added. The reaction is stirred overnight, gradually warming to room temperature. To the solution is then added 30 mL saturated ammonium chloride. The reaction mixture is stirred for 10 minutes, during which time the aqueous layer turns blue. The reaction mixture is then extracted with hexanes, and the combined organic layers are dried over magnesium sulfate. The solvent is carefully removed by rotary evaporation to give 17 g of a colorless, malodorous liquid.

المصدر